Histone H3 (mono methyl R2)Antibody (YA370)
Histone H3 (mono methyl R2)Antibody (YA370) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H3 (mono methyl R2).
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse
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Formulation:
Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000 | 1:50-1:200 |
Product Details
Histone H3 (mono methyl R2)Antibody (YA370) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H3 (mono methyl R2).
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 15 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 15 kDa
Entrez Gene: 8350 Human ; 8351 Human ; 8352 Human ; 8353 Human ; 8354 Human ; 8355 Human ; 8356 Human ; 8357 Human ; 8358 Human ; 8968 Human ; 319152 Mouse ; 319153 Mouse ; 360198 Mouse ; 97908 Mouse ;
SwissProt: P68431 Human ; P84243 Human ; Q6NXT2 Human ; Q71DI3 Human ; Q16695 Human ; P84228 Mouse ; P68433 Mouse ;
OMIM: 137800 Human
Synthetic peptide corresponding to Human Histone H3.AA range:1-49.
Endogenous
Protein A affinity purified.
Non-conjugated
Methylated
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Histone H3 core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
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Subcellular Localization
Nucleus; Chromosome
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Subunit
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Interacts with TONSL; CHAF1A; CHAF1B; MCM2 and DNAJC9 (PubMed:33857403). Interacts with NASP; NASP is a histone chaperone that stabilizes and maintains a soluble pool of Histone H3-H4 dimers (PubMed:22195965)
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SwissProt ID
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Research Field
Epigenetics and Nuclear Signaling
Documentation
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