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  5. Human CD138 Antibody (PE)(YA3444)

Human CD138 Antibody (PE)(YA3444)

Cat. No.: HY-P83707M
User Guide for Antibodies Technical Support

Human CD138 Antibody (PE)(YA3444) is a PE-conjugated, mouse-derived and phycoerythrin (PE) IgG1 monoclonal antibody, targeting to CD138.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

Human CD138 Antibody (PE)(YA3444) is a PE-conjugated, mouse-derived and phycoerythrin (PE) IgG1 monoclonal antibody, targeting to CD138.
Host

Mouse
Clonality

Monoclonal
Molecular Weight
Predicted band size: 41 kDa;
Observed band size: 50 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from Human CD183.
Application &
Dilution Ratio
Application Dilution Ratio
FC
FC: Flow Cytometry
5μL per test for million cells or whole blood in 100 μL volume.
Purity Affinity Conjugation PE
Modification Unmodified Isotype IgG1
Appearance

Liquid
Formulation

Supplied in PBS、0.5%BSA、0.03%PC-300.
Storage & Stability

Stored at 2-8°C for 1 year, protect from light, do not freeze.
Shipping

Shipping with blue ice.
Background
Function：Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway (PubMed:12782716). Binds to CCL21. Probably promotes cell chemotaxis response. Upon activation by PF4, induces activated T-lymphocytes migration mediated via downstream Ras/extracellular signal-regulated kinase (ERK) signaling; Receptor for the C-X-C chemokine CXCL4 and also mediates the inhibitory activities of CXCL9, CXCL10 and CXCL11 on the proliferation, survival and angiogenic activity of human microvascular endothelial cells (HMVEC) through a cAMP-mediated signaling pathway (PubMed:12782716). Does not promote cell chemotaxis respons. Interaction with CXCL4 or CXCL10 leads to activation of the p38MAPK pathway and contributes to inhibition of angiogenesis. Overexpression in renal cancer cells down-regulates expression of the anti-apoptotic protein HMOX1 and promotes apoptosis; Mediates the activity of CXCL11
Subcellular Localization：Cell membrane; Multi-pass membrane protein; Cell membrane; Multi-pass membrane protein
Expression：
Tissue_specificity:Isomer 1 and isomer 2 are primarily expressed in the heart, kidneys, liver, and skeletal muscle. Isomer 1 is also expressed in the placenta. Isomer 2 is expressed in endothelial cells. It is also expressed in T cells (protein level) .
Isoforms & Post-Translational Modification：P49682 has 3 isomers: P49682-1: 40660 Da (predicted); P49682-2: 45523 Da (predicted); P49682-3: 28715 Da (predicted).
Sulfation on Tyr-27 and Tyr-29 is essential for CXCL10 binding and subsequent signal transduction induction;N-glycosylated
Subunit：Homomer. Forms heteromers with ACKR4
Database

Entrez Gene: 2833 Human

SwissProt: P49682 Human

OMIM: 300574 Human

Synonyms
CD_antigen antibody; CD138 antibody; CD138 antigen antibody; heparan sulfate proteoglycan fibroblast growth factor receptor antibody; SDC antibody; Sdc1 antibody; SDC1_HUMAN antibody; SYND1 antibody; Syndecan 1 antibody; Syndecan antibody; syndecan proteoglycan 1 antibody; Syndecan-1 antibody
Documentation
User Guide for Antibodies (1077 KB)

Human CD138 Antibody (PE)(YA3444) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Human CD138 Antibody (PE)(YA3444)
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