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IL-13 Receptor alpha 1 Antibody (YA1624)

(Synonyms: IL13RA1; IL13R; IL13RA; Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1)
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Based on 1 Customer Validation

IL-13 Receptor alpha 1 Antibody (YA1624) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-13 Receptor alpha 1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB

  • Reactivity :

    Human

  • Formulation:

    Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

  • Conjugation:
    Non-conjugated
  • Experimental Validation Results for IL-13 Receptor alpha 1 Antibody (YA1624)
  • IL-13 Receptor alpha 1 Antibody (YA1624) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:500-1:1000

Product Details

Description

IL-13 Receptor alpha 1 Antibody (YA1624) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-13 Receptor alpha 1.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 49 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 49 kDa
Species Reactivity Database

Entrez Gene: 3597 Human

SwissProt: P78552 Human

Immunogen

A synthesized peptide derived from human IL13 receptor alpha 1 aa50-101/427.

Sensitivity

Endogenous

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

RRID

AB_3103976

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for IL-13 Receptor alpha 1 Antibody (YA1624)
    Western blot analysis of extracts from A549(lane 2(20μg) and A549(lane 3(40ug)using IL-13 Receptor alpha 1 Antibody (HY-P80879) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

Background

  • Function

    IL-13 Receptor alpha 1 binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity

  • Subcellular Localization

    Membrane; Single-pass type I membrane protein

  • Expression


    Tissue_specificity:It is widely distributed. The highest concentrations are found in the heart, liver, skeletal muscle, and ovaries; the lowest concentrations are found in the brain, lungs, and kidneys. It is also present in B cells, T cells, and endothelial cells.

  • Isoforms & Post-Translational Modification

    P78552 has 2 isomers: P78552-1: 48760 Da (predicted); P78552-2: 31659 Da (predicted).

  • Subunit

    Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. Interacts with TRAF3IP1. Interacts with IL4 (PubMed:18243101)

  • SwissProt ID

    P78552

  • Gene ID
    3597 [NCBI]
  • Synonyms

    IL13RA1; IL13R; IL13RA; Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1

  • Research Field

    Immunology

IL-13 Receptor alpha 1 Antibody (YA1624) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • 1/16

    MedChemExpress Validation
     Western blot analysis of extracts from A549(lane 2(20μg) and A549(lane 3(40ug)using IL-13 Receptor alpha 1 Antibody (HY-P80879) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

  • IL-13 Receptor alpha 1 Antibody (YA1624) Product Image
    1/16
  • Experimental Validation Results for IL-13 Receptor alpha 1 Antibody (YA1624)
  • IL-13 Receptor alpha 1 Antibody (YA1624) Product Image
  • Experimental Validation Results for IL-13 Receptor alpha 1 Antibody (YA1624)
    1/1
    MedChemExpress Validation
     Western blot analysis of extracts from A549(lane 2(20μg) and A549(lane 3(40ug)using IL-13 Receptor alpha 1 Antibody (HY-P80879) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
  • Experimental Validation Results for IL-13 Receptor alpha 1 Antibody (YA1624)
  • IL-13 Receptor alpha 1 Antibody (YA1624) Product Image
    MedChemExpress Validation

    Western blot analysis of extracts from A549(lane 2(20μg) and A549(lane 3(40ug)using IL-13 Receptor alpha 1 Antibody (HY-P80879) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

  • IL-13 Receptor alpha 1 Antibody (YA1624) Product Image WB