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  4. Monoclonal Antibodies Recombinant Antibodies
  5. IL-13 Receptor alpha 1 Antibody (YA1624)

IL-13 Receptor alpha 1 Antibody (YA1624)

Cat. No.: HY-P81879
COA
SDS
User Guide for Antibodies Technical Support

IL-13 Receptor alpha 1 Antibody (YA1624) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-13 Receptor alpha 1.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

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  • Descripciòn

Descripciòn

IL-13 Receptor alpha 1 Antibody (YA1624) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-13 Receptor alpha 1.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Peso molecular
Predicted band size: 49 kDa;
Observed band size: 49 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human IL13 receptor alpha 1 aa50-101/427.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
Sensitivity Endogenous Pureza Affinity Chromatography
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Envío

Shipping with blue ice.
Verification Image
WB

  • Western blot analysis of extracts from A549(lane 2(20μg) and A549(lane 3(40ug)using IL-13 Receptor alpha 1 Antibody (HY-P80879) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

Background
Function：Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity
Subcellular Localization：Membrane; Single-pass type I membrane protein
Expression：
Tissue_specificity:It is widely distributed. The highest concentrations are found in the heart, liver, skeletal muscle, and ovaries; the lowest concentrations are found in the brain, lungs, and kidneys. It is also present in B cells, T cells, and endothelial cells.
Isoforms & Post-Translational Modification：P78552 has 2 isomers: P78552-1: 48760 Da (predicted); P78552-2: 31659 Da (predicted).
Subunit：Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. Interacts with TRAF3IP1. Interacts with IL4 (PubMed:18243101)
RRID
Database

Entrez Gene: 3597 Human

SwissProt: P78552 Human

OMIM: 300119 Human

Research Field

Immunology
Synonyms
IL13RA1; IL13R; IL13RA; Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1
Documentación
SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

IL-13 Receptor alpha 1 Antibody (YA1624) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
IL-13 Receptor alpha 1 Antibody (YA1624)
Cat. No.:
HY-P81879
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