KIAA1609 Antibody (YA8489)(PBS only)
(Synonyms: KIAA1609)KIAA1609 Antibody (YA8489) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to KIAA1609.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
WB, ICC/IF, FC
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:2000-3000 | 1:100-250 | 1:100 |
Product Details
KIAA1609 Antibody (YA8489) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to KIAA1609.
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Host Mouse
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 50.8 kDa
Full length human recombinant protein of human KIAA1609 produced in HEK293T cell.
Affinity purified
Non-conjugated
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
KIAA1609 activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration. Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome[1].
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Subcellular Localization
Membrane,Cytoplasm,Lysosome
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Expression
Induction: Addition of nutrients and insulin induces its expression (at protein level)
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Isoforms & Post-Translational Modification
Q6P9B6: 456 amino acids, molecular weight 50994 Da.
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Subunit
Interacts (via C-terminal domain) with MTOR and MLST8; the interaction with MTOR increases upon nutrient stimulation
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SwissProt ID
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Synonyms
KIAA1609
Documentation
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