Laminin alpha 3 Antibody (YA1548)

Cat. No.: HY-P81803: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

Laminin alpha 3 Antibody (YA1548) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Laminin alpha 3.

For research use only. We do not sell to patients.

Size	Stock	Quantity
Free Sample	Apply now
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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Laminin alpha 3 Antibody (YA1548) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Laminin alpha 3 Antibody (YA1548) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Laminin alpha 3.

Host

Rabbit

Clonality

Recombinant, Monoclonal

Molecular Weight

Predicted band size: 367 kDa;

Observed band size: 367 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q16787

Gene ID

3909 [NCBI]

Immunogen

A synthesized peptide derived from human LAMA3 aa92-143.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Sensitivity	Endogenous	Purity	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components; Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes

Subcellular Localization：Secreted, extracellular space, extracellular matrix, basement membrane

Expression：
Tissue_specificity:Skin; respiratory, urinary, and digestive epithelia and in other specialized tissues with prominent secretory or protective functions. Epithelial basement membrane, and epithelial cell tongue that migrates into a wound bed. A differential and focal expression of the subunit alpha-3 is observed in the CNS

Induction:Laminin-5 is up-regulated in wound sites of human skin

Isoforms & Post-Translational Modification：Q16787 has 4 isomers: Q16787-2: 366619 Da (predicted); Q16787-1: 190461 Da (predicted); Q16787-3: 360182 Da (predicted); Q16787-4: 184024 Da (predicted).

Subunit：Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end.

RRID

AB_3103904

Database

Entrez Gene: 3909 Human

SwissProt: Q16787 Human

OMIM: 619783 Human

Research Field

Cardiovascular

Synonyms

LAMA3; Laminin 5 alpha3; E170; LAMNA; LOCS; laminin alpha 3; Laminin A3

Documentation

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

Laminin alpha 3 Antibody (YA1548) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Laminin alpha 3 Antibody (YA1548)

Laminin alpha 3 Antibody (YA1548) Featured Recommendations:

Product Detail

Background

Documentation

Laminin alpha 3 Antibody (YA1548) Related Classifications

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