Laminin beta 1 Antibody (YA4946)(PBS only)
(Synonyms: LAMB1; Laminin subunit beta-1; Laminin B1 chain; Laminin-1 subunit beta; Laminin-10 subunit beta; Laminin-12 subunit beta; Laminin-2 subunit beta; Laminin-6 subunit beta; Laminin-8 subunit beta)Laminin beta 1 Antibody (YA4946) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Laminin beta 1.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:10000 |
Product Details
Laminin beta 1 Antibody (YA4946) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Laminin beta 1.
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Host Mouse
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 198 kDa;
Purified recombinant fragment of LAMB1 (aa31-270) expressed in E. Coli. The exact sequence is proprietary to MCE.
affinity purified
Non-conjugated
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Laminin beta 1 is a Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface
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Subcellular Localization
Secreted, extracellular space, extracellular matrix, basement membrane
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Subunit
Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma).
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SwissProt ID
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Synonyms
LAMB1; Laminin subunit beta-1; Laminin B1 chain; Laminin-1 subunit beta; Laminin-10 subunit beta; Laminin-12 subunit beta; Laminin-2 subunit beta; Laminin-6 subunit beta; Laminin-8 subunit beta
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