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LIFR Antibody (YA6636)

(Synonyms: CD118 antibody; CD118 antigen antibody; FLJ98106 antibody; FLJ99923 antibody; Leukemia inhibitory factor receptor alpha antibody; Leukemia inhibitory factor receptor antibody; LIF R antibody; LIF receptor antibody; LIF-R antibody; Lifr antibody; CD118 antibody; CD118 antigen antibody; FLJ98106 antibody; FLJ99923 antibody; Leukemia inhibitory factor receptor alpha antibody; Leukemia inhibitory factor receptor antibody; LIF R antibody; LIF receptor antibody; LIF-R antibody; Lifr antibody; LIFR_HUMAN antibody; SJS2 antibody; STWS antibody; SWS antibody; )
Customer Review

Based on 1 Customer Validation

LIFR Antibody (YA6636) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LIFR.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Conjugation:
    Non-conjugated
  • Experimental Validation Results for LIFR Antibody (YA6636)
  • LIFR Antibody (YA6636) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:2000

Product Details

Description

LIFR Antibody (YA6636) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LIFR.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 180 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 124 kDa
Immunogen

Recombinant protein within human LIFR aa 1-850.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for LIFR Antibody (YA6636)
    Western blot analysis of extracts from Human breast cancer (lane 1(40μg)) 、Human colon cancer (lane 2(40μg, negative)) and Human kidney (lane 3(40μg)) using LIFR Antibody (HY-P86943) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/2000) and Loading control antibody (β Tubulin, 1/10000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.

Background

  • Function

    LIFR is a Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells

  • Subcellular Localization

    Cell membrane,Secreted

  • Isoforms & Post-Translational Modification

    P42702 has two isomers: P42702-1: 123743 Da (predicted); P42702-2: Da (predicted).

  • Subunit

    Heterodimer composed of LIFR and IL6ST

  • SwissProt ID

    P42702

  • Gene ID
    3977 [NCBI]
  • Synonyms

    CD118 antibody; CD118 antigen antibody; FLJ98106 antibody; FLJ99923 antibody; Leukemia inhibitory factor receptor alpha antibody; Leukemia inhibitory factor receptor antibody; LIF R antibody; LIF receptor antibody; LIF-R antibody; Lifr antibody; CD118 antibody; CD118 antigen antibody; FLJ98106 antibody; FLJ99923 antibody; Leukemia inhibitory factor receptor alpha antibody; Leukemia inhibitory factor receptor antibody; LIF R antibody; LIF receptor antibody; LIF-R antibody; Lifr antibody; LIFR_HUMAN antibody; SJS2 antibody; STWS antibody; SWS antibody;

LIFR Antibody (YA6636) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • 1/16

    MedChemExpress Validation
     Western blot analysis of extracts from Human breast cancer (lane 1(40μg)) 、Human colon cancer (lane 2(40μg, negative)) and Human kidney (lane 3(40μg)) using LIFR Antibody (HY-P86943) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/2000) and Loading control antibody (β Tubulin, 1/10000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.

  • LIFR Antibody (YA6636) Product Image
    1/16
  • Experimental Validation Results for LIFR Antibody (YA6636)
  • LIFR Antibody (YA6636) Product Image
  • Experimental Validation Results for LIFR Antibody (YA6636)
    1/1
    MedChemExpress Validation
     Western blot analysis of extracts from Human breast cancer (lane 1(40μg)) 、Human colon cancer (lane 2(40μg, negative)) and Human kidney (lane 3(40μg)) using LIFR Antibody (HY-P86943) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/2000) and Loading control antibody (β Tubulin, 1/10000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.
  • Experimental Validation Results for LIFR Antibody (YA6636)
  • LIFR Antibody (YA6636) Product Image
    MedChemExpress Validation

    Western blot analysis of extracts from Human breast cancer (lane 1(40μg)) 、Human colon cancer (lane 2(40μg, negative)) and Human kidney (lane 3(40μg)) using LIFR Antibody (HY-P86943) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/2000) and Loading control antibody (β Tubulin, 1/10000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.

  • LIFR Antibody (YA6636) Product Image WB