LILRA3 Antibody (YA7115)(PBS only)
(Synonyms: CD85e, ILT6, LIR4, LILRA3, Leukocyte immunoglobulin-like receptor subfamily A member 3, CD85 antigen-like family member E, Immunoglobulin-like transcript 6, Leukocyte immunoglobulin-like receptor 4, Monocyte inhibitory receptor HM43/HM31, ILT-6, LIR-4)LILRA3 Antibody (YA7115) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LILRA3.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
FC, ELISA
-
Reactivity :
Human
-
Formulation:
Supplied in PBS, pH 7.4.
-
Conjugation:
Non-conjugated
Applications
| Application |
FC
FC: Flow Cytometry
|
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|
| Dilution Ratio | 1:200-1:400 | 1:10000 |
Product Details
LILRA3 Antibody (YA7115) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LILRA3.
-
Host Mouse
-
Species ReactivityHuman
-
Calculated Molecular Weight Predicted band size: 47.5kDa;
Purified recombinant fragment of human LILRA3 (AA: 24-168) expressed in E. Coli.
affinity purified.
Non-conjugated
IgG1
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS, pH 7.4.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
LILRA3 acts as a soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes
-
Subcellular Localization
Secreted
-
Expression
Tissue_Specificity: Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung -
Isoforms & Post-Translational Modification
Q8N6C8 has three isomers: Q8N6C8-1: 47472 Da (predicted); Q8N6C8-2: 40357 Da (predicted); Q8N6C8-3: 49187 Da (predicted).
N-glycosylation is required for ligand binding -
SwissProt ID
-
Synonyms
CD85e, ILT6, LIR4, LILRA3, Leukocyte immunoglobulin-like receptor subfamily A member 3, CD85 antigen-like family member E, Immunoglobulin-like transcript 6, Leukocyte immunoglobulin-like receptor 4, Monocyte inhibitory receptor HM43/HM31, ILT-6, LIR-4
Documentation