LILRA3 Antibody (YA7115)
LILRA3 Antibody (YA7115) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LILRA3.
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Host:
Mouse
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Isotype:
IgG1
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Application:
FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:400 | 1:10000 |
Product Details
LILRA3 Antibody (YA7115) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LILRA3.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 47.5kDa;
SwissProt: SwissProt: Q8N6C8
Purified recombinant fragment of human LILRA3 (AA: 24-168) expressed in E. Coli.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
LILRA3 acts as a soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes
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Subcellular Localization
Secreted
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Expression
Tissue_Specificity: Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung -
Isoforms & Post-Translational Modification
Q8N6C8 has three isomers: Q8N6C8-1: 47472 Da (predicted); Q8N6C8-2: 40357 Da (predicted); Q8N6C8-3: 49187 Da (predicted).
N-glycosylation is required for ligand binding -
SwissProt ID
Documentation
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