2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. MCJ Antibody (YA2982)

MCJ Antibody (YA2982) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MCJ.

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Descripciòn

Descripciòn

MCJ Antibody (YA2982) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MCJ.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Peso molecular
Predicted band size: 16 kDa;
Observed band size: 16 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human DNAJC15 aa50-150.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-1:100
Sensitivity Endogenous Pureza Affinity Chromatography
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Envío

Shipping with blue ice.
Background
Function：Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP (By similarity). Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9
Subcellular Localization：Mitochondrion inner membrane; Single-pass membrane protein
Expression：
Tissue_specificity:Expressed at highest levels in heart, followed by liver and kidney
Subunit：Interacts with the TIM23 complex. Directly interacts with PAM16/MAGMAS; this interaction counteracts DNAJC15-dependent stimulation of HSPA9 ATPase activity. Associates with complex I of the mitochondrial electron transfer chain; this interaction may interfere with the formation of supercomplexes that facilitate the transfer of electrons between complexes (By similarity)
RRID
Database

Entrez Gene: 29103 Human ;

SwissProt: Q9Y5T4 Human ;

OMIM: 615339 Human

Research Field

Signal Transduction
Synonyms
HSD18; MCJ; Methylation controlled J protein; DNAJC15; DNAJD1; GIG22; DJC1
Documentación
SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

MCJ Antibody (YA2982) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
MCJ Antibody (YA2982)
Cat. No.:
HY-P83237
Cantidad:
MCE Japan Authorized Agent:

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Observaciones

SAFETY DATA SHEET (SDS)

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