Mesothelin Antibody (YA5652)

Cat. No.: HY-P85960: Data Sheet User Guide for Antibodies
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Mesothelin Antibody (YA5652) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Mesothelin.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

Mesothelin Antibody (YA5652) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Mesothelin.

Host

Mouse

Clonality

Monoclonal

분자량

Predicted band size: 69 kDa;

Observed band size: 65 kDa,45 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q13421

Gene ID

10232 [NCBI]

Immunogen

Synthesized peptide derived from human Mesothelin AA range: 400-500

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1000
WB WB: Western Blot	1:500-2000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-500
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:1000-5000

Purity	Protein G	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG2b

Appearance

Liquid

Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Membrane-anchored forms may play a role in cellular adhesion; Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro

Subcellular Localization：Cell membrane; Lipid-anchor, GPI-anchor; Golgi apparatus; Secreted; Secreted

Expression：
Tissue_specificity:It is expressed in the lungs. It is expressed at low levels in the heart, placenta, and kidneys. It is expressed in mesothelial cells. It is highly expressed (protein level) in mesothelioma, ovarian cancer, and certain squamous cell carcinomas.

Isoforms & Post-Translational Modification：Q13421 has 4 isomers: Q13421-1: 68986 Da (predicted); Q13421-3: 68070 Da (predicted); Q13421-2: 71492 Da (predicted); Q13421-4: 67940 Da (predicted).
Both MPF and the cleaved form of mesothelin are N-glycosylated;Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin

Subunit：Interacts with MUC16

Synonyms

Mesothelin; CAK1 antigen; Pre-pro-megakaryocyte-potentiating factor; [Cleaved into: Megakaryocyte-potentiating factor; MPF; Mesothelin, cleaved form]

각종 서류

User Guide for Antibodies (1077 KB)