MLF1 (Myeloid leukemia factor 1) Antibody (YA8197)

Cat. No.: HY-P88513: Data Sheet User Guide for Antibodies
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MLF1 (Myeloid leukemia factor 1) Antibody (YA8197) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MLF1 (Myeloid leukemia factor 1).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

MLF1 (Myeloid leukemia factor 1) Antibody (YA8197) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MLF1 (Myeloid leukemia factor 1).

Host

Mouse

Clonality

Monoclonal

분자량

Predicted band size: 30.4 kDa

Species Reactivity

Human

SwissProt ID

P58340

Immunogen

Full length human recombinant protein of human MLF1 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus

Subcellular Localization：Cytoplasm,Nucleus,Cell projection, cilium,Cytoplasm, cytoskeleton, cilium basal body

Expression：
Tissue_Specificity: Most abundant in testis, ovary, skeletal muscle, heart, kidney and colon. Low expression in spleen, thymus and peripheral blood leukocytes

Isoforms & Post-Translational Modification：P58340 has 5 isomers: P58340-1: 30627 Da (predicted); P58340-2: 23117 Da (predicted); P58340-3: 33888 Da (predicted); P58340-5: 27625 Da (predicted); P58340-4: 29095 Da (predicted).
Phosphorylation is required for binding to YWHAZ

Subunit：Interacts with CENPU

Synonyms

myeloid leukemia factor 1; myeloid leukemia factor 1 variant 1; myeloid leukemia factor 1 variant 2; myeloid leukemia factor 1 variant 3

각종 서류

User Guide for Antibodies (1077 KB)