MonoMethyl-Histone H3 Antibody (YA998)
(Synonyms: H3K14me; H3.4; H3/g; H3FT; H3t)MonoMethyl-Histone H3 Antibody (YA998) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MonoMethyl-Histone H3.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:200 |
Product Details
MonoMethyl-Histone H3 Antibody (YA998) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MonoMethyl-Histone H3.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 16 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 16 kDa
A synthetic peptide of human MonoMethyl-Histone H3-K14 GG-(Me)K-AP.
Endogenous
Affinity Purified
Non-conjugated
Methylated
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MonoMethyl-Histone H3 core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
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Subcellular Localization
Nucleus; Chromosome
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Expression
Tissue_specificity:Expressed in testicular cells -
Subunit
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Interacts with TONSL; CHAF1A and CHAF1B (PubMed:33857403)
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SwissProt ID
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Synonyms
H3K14me; H3.4; H3/g; H3FT; H3t
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Research Field
Epigenetics and Nuclear Signaling
Documentation
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