Mucin 5B Antibody (YA9793)
(Synonyms: MG1, MUC5, MUC5B, MUC9, Mucin 5B, 2300002I04Rik, A130042M24, AV085033,)
Based on 1 Customer Validation
Mucin 5B Antibody (YA9793) is a Rabbit-derived and non-conjugated IgG Monoclonal antibody, targeting to Mucin 5B.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, FC
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Reactivity :
Human
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Formulation:
Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-100 |
Product Details
Mucin 5B Antibody (YA9793) is a Rabbit-derived and non-conjugated IgG Monoclonal antibody, targeting to Mucin 5B.
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Host Rabbit
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 596 kDa;
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 596 kDa
Synthesized peptide derived from human MUC5B
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Mucin 5B is a Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus
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Subcellular Localization
Secreted
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Expression
Tissue_Specificity: Expressed on surface airway epithelia. Expressed mainly in mucous cells of submucosal glands of airway tissues. Highly expressed in the sublingual gland. Also found in submaxillary glands, endocervix, gall bladder, and pancreas.
Induction: Regulated by all-trans-retinoic acid (ATRA) in a cell-type specific manner. -
Isoforms & Post-Translational Modification
Mucin 5B has an amino acid length of 5762, molecular weight is 596340 Da.
Highly glycosylated. C-, N- and O-glycosylated. C-mannosylated in the Cys-rich subdomains probably on the first Trp residue of the WXXW motif. Highly O-glycosylated in the Ser/Thr-rich tandem repeat (TR) region. The repeat region is about 59% O-glycosylated with a high abundance of NeuAc(2)Hex(1)HexNac1-ol. -
Subunit
Homomultimer; disulfide-linked.
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SwissProt ID
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Synonyms
MG1, MUC5, MUC5B, MUC9, Mucin 5B, 2300002I04Rik, A130042M24, AV085033,
Documentation
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