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MyoD1/Myf3 Antibody (YA3805)(PBS only)

(Synonyms: PUM; MYF3; MYOD; bHLHc1; MYODRIF)

MyoD1/Myf3 Antibody (YA3805) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MyoD1/Myf3.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    ICC/IF, FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • MyoD1/Myf3 Antibody (YA3805)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:50-1:200 1:200-1:400 1:10000

Product Details

Description

MyoD1/Myf3 Antibody (YA3805) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MyoD1/Myf3.

  • Host Mouse
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 35 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 35 kDa
Immunogen

Purified recombinant fragment of human MYOD1 (AA: 221-320) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    MyoD1/Myf3 acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins

  • Subcellular Localization

    Nucleus

  • Subunit

    Efficient DNA binding requires dimerization with another bHLH protein. Seems to form active heterodimers with ITF-2. Interacts with SUV39H1.

  • SwissProt ID

    P15172

  • Gene ID
    4654 [NCBI]
  • Synonyms

    PUM; MYF3; MYOD; bHLHc1; MYODRIF

MyoD1/Myf3 Antibody (YA3805)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • MyoD1/Myf3 Antibody (YA3805)(PBS only) Product Image