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Cat. No.: HY-P88099A

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NAPEPLD (NAPE-PLD) Antibody (YA7783)(PBS only)

(Synonyms: FMP30; NAPE-PLD)

NAPEPLD (NAPE-PLD) Antibody (YA7783) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to NAPEPLD (NAPE-PLD).

For research use only. We do not sell to patients.

Host:
Mouse
Isotype:
IgG2a
Application:
IHC-P, ICC/IF, FC
Reactivity :
Human, Mouse, Rat

Formulation:
Supplied in PBS, pH 7.4.

Conjugation:
Non-conjugated

Size

Price

Stock

Quantity

Sample (0.1mg)

In-stock

(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications
Product Details
Product Properties
- Appearance
- Formulation
- Storage & Stability
- Shipping
Background
Documentation
Help & FAQs
Bioz

Applications

Application	IHC-P IHC-P: Immunohistochemistry-Paraffin	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence	FC FC: Flow Cytometry
Dilution Ratio	1:150-500	1:100-250	1:100

Product Details

Description

NAPEPLD (NAPE-PLD) Antibody (YA7783) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to NAPEPLD (NAPE-PLD).

Host Mouse
Species Reactivity
Human, Mouse, Rat
Calculated Molecular Weight Predicted band size: 45.4 kDa

Immunogen

Full length human recombinant protein of human NAPEPLD produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG2a

Product Properties

Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Background

Function

D-type phospholipase that hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce bioactive N-acylethanolamines/fatty acid ethanolamides (NAEs/FAEs) and phosphatidic acid (PubMed:14634025, PubMed:16527816, PubMed:25684574, PubMed:27571266). Cleaves the terminal phosphodiester bond of diacyl- and alkenylacyl-NAPEs, primarily playing a role in the generation of long-chain saturated and monounsaturated NAEs in the brain (By similarity). May control NAPE homeostasis in dopaminergic neuron membranes and regulate neuron survival, partly through RAC1 activation (By similarity). As a regulator of lipid metabolism in the adipose tissue, mediates the crosstalk between adipocytes, gut microbiota and immune cells to control body temperature and weight. In particular, regulates energy homeostasis by promoting cold-induced brown or beige adipocyte differentiation program to generate heat from fatty acids and glucose. Has limited D-type phospholipase activity toward N-acyl lyso-NAPEs (By similarity)
Subcellular Localization

Golgi apparatus membrane,Early endosome membrane,Nucleus envelope,Nucleus, nucleoplasm
Expression

Tissue_Specificity: Widely expressed. Highest expression in brain, kidney and testis (at protein level). Expressed in adipose tissue (at protein level)
Isoforms & Post-Translational Modification

Q6IQ20: 393 amino acids, molecular weight 45596 Da.
Subunit

Homodimer
SwissProt ID

Q6IQ20
Synonyms

FMP30; NAPE-PLD