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Cat. No.: HY-P87612

NCS1 Antibody (YA7296)

NCS1 Antibody (YA7296) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NCS1.

For research use only. We do not sell to patients.

Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

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Stock

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	IHC-P IHC-P: Immunohistochemistry-Paraffin	IHC-F IHC-F: Immunohistochemistry-Frozen	IF-Tissue IF-Tissue: Immunofluorescence-Tissue	FC FC: Flow Cytometry
Dilution Ratio	1:500-2000	1:100-500	1:100-500	1:100-500	1:50-100

Description

NCS1 Antibody (YA7296) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NCS1.

Host Rabbit
Clonality Recombinant,Monoclonal
Species Reactivity
Human, Mouse, Rat
Observed Molecular Weight

Observed band size: 22 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 22 kDa

Immunogen

A synthesized peptide derived from human NCS 1

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

NCS1 is a Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin. Stimulates PI4KB kinase activity. Involved in long-term synaptic plasticity through its interaction with PICK1. May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel
Subcellular Localization

Golgi apparatus,Postsynaptic density,Cytoplasm, perinuclear region,Cytoplasm,Cell membrane,Membrane
Isoforms & Post-Translational Modification

P62166 has two isomers: P62166-1: 21879 Da (predicted); P62166-2: 19728 Da (predicted).
Subunit

Monomer (By similarity)
SwissProt ID

P62166