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  3. Primary Antibodies
  4. Polyclonal Antibodies Flow Cytometry Antibodies
  5. NCX1 Antibody

NCX1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to NCX1.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

NCX1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to NCX1.
Host

Rabbit
Clonality

polyclonal
Molecular Weight

Predicted band size: 106kDa;
Species Reactivity
Human, Mouse, Rat, GuineaPig
SwissProt ID
Immunogen

KLH conjugated synthetic peptide derived from human NCX1
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-2000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:100-500
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
100-500
FC
FC: Flow Cytometry
0.2 ug/test
Sensitivity Endogenous Purity affinity purified.
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Solution
Formulation

Supplied in 0.01M TBS(PH7.4), with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes (PubMed:11241183, PubMed:1374913, PubMed:1476165). Contributes to Ca(2+) transport during excitation-contraction coupling in muscle (PubMed:11241183, PubMed:1374913, PubMed:1476165). In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum (PubMed:11241183, PubMed:1374913, PubMed:1476165). SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline (PubMed:11241183, PubMed:1374913, PubMed:1476165). Required for normal embryonic heart development and the onset of heart contractions (By similarity)
Subcellular Localization：Cell membrane; Multi-pass membrane protein
Expression：
Tissue_specificity:Detected primarily in heart and at lower levels in brain (PubMed:1374913) . Expressed in cardiac sarcolemma, brain, kidney, liver, pancreas, skeletal muscle, placenta and lung (PubMed:1476165)
Isoforms & Post-Translational Modification：P32418 has 5 isomers: P32418-1: 108547 Da (predicted); P32418-2: 104689 Da (predicted); P32418-3: 107242 Da (predicted); P32418-4: 107850 Da (predicted); P32418-5: 107938 Da (predicted).
Synonyms
Na+/Ca2+exchanger 1, CNC, DKFZp779F0871, MGC119581, FLJ37694, FLJ43417, Na+/Ca2+ exchange protein 1, Na+/Ca2+ exchanger, NCX 1, NCX, SLC8A1, SLC8A1 protein, Sodium Calcium Exchanger, Sodium/calcium exchanger 1, Solute carrier family 8 member 1, NAC1_HUMAN.
Documentation
User Guide for Antibodies (1077 KB)

NCX1 Antibody Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NCX1 Antibody
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HY-P810517
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