country

Change Language

Country or Region:

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-P85580

Noggin Antibody (YA5272)

Name: Noggin Antibody (YA5272)
Brand: MedChemExpress
SKU: HY-P85580
Availability: PreOrder

(Synonyms: NOG; NOGG_HUMAN; Noggin; SYM 1; SYM1; Symphalangism 1; proximal; Synostoses; multiple; syndrome 1; SYNS 1; SYNS1.)

Noggin Antibody (YA5272) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Noggin.

For research use only. We do not sell to patients.

Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence
Dilution Ratio	1:1000	1:100

Description

Noggin Antibody (YA5272) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Noggin.

Host Mouse
Clonality Monoclonal
Observed Molecular Weight

Observed band size: 26 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Immunogen

Purified recombinant human Noggin protein fragments expressed in E.coli.

Sensitivity

Transfected

Purification

affinity chromatography.

Conjugation

Non-conjugated

Modification

Unmodified

Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

Noggin is an Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6^[1]^[2].
Subcellular Localization

Secreted
Subunit

Homodimer. Interacts with GDF5; inhibits chondrocyte differentiation
SwissProt ID

Q13253
Gene ID

9241 [NCBI]
Synonyms

NOG; NOGG_HUMAN; Noggin; SYM 1; SYM1; Symphalangism 1; proximal; Synostoses; multiple; syndrome 1; SYNS 1; SYNS1.