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NUCB1 (Nucleobindin 1) Antibody (YA8011)(PBS only)

(Synonyms: CALNUC; NUC)

NUCB1 (Nucleobindin 1) Antibody (YA8011) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NUCB1 (Nucleobindin 1).

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P, ICC/IF, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • NUCB1 (Nucleobindin 1) Antibody (YA8011)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:150-500 1:100-250 1:100

Product Details

Description

NUCB1 (Nucleobindin 1) Antibody (YA8011) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NUCB1 (Nucleobindin 1).

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 53.7 kDa
Immunogen

Full length human recombinant protein of human NUCB1 produced in HEk293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    NUCB1 is a Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins)

  • Subcellular Localization

    Golgi apparatus, cis-Golgi network membrane,Cytoplasm,Secreted

  • Expression


    Tissue_Specificity: Expressed both in fetal and adult heart, lung, liver, kidney and brain, and in adult skeletal muscle, placenta and pancreas

  • Isoforms & Post-Translational Modification

    Q02818: 461 amino acids, molecular weight 53879 Da.

  • Subunit

    Interacts (via GBA motif) with guanine nucleotide-binding protein G(i) alpha subunits GNAI1, GNAI2 and GNAI3 with higher affinity for GNAI1 and GNAI3 than for GNAI2

  • SwissProt ID

    Q02818

  • Synonyms

    CALNUC; NUC

NUCB1 (Nucleobindin 1) Antibody (YA8011)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • NUCB1 (Nucleobindin 1) Antibody (YA8011)(PBS only) Product Image