NUP107 Antibody (YA9777)
(Synonyms: Nucleoporin 107, Nuclear Pore Complex Protein Nup107, NUP84, Nucleoporin 107kDa, 107 KDa Nucleoporin, Nucleoporin Nup107, ODG6, GAMOS7, NPHS11, ODG6)NUP107 Antibody (YA9777) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to NUP107.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, FC, ICC/IF
-
Reactivity :
Human, rat
-
Formulation:
Supplied in PBS (pH 7.4) containing 50% glycerol, 0.05% BSA and 0.02% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
FC
FC: Flow Cytometry
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-5000 | 1:200-2000 | 1:100-1000 |
Product Details
NUP107 Antibody (YA9777) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to NUP107.
-
Host Rabbit
-
Species ReactivityHuman, rat
-
Observed Molecular WeightObserved band size: 106 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 106 kDa
A synthesized peptide derived from human Nup107
affinity purified.
Non-conjugated
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS (pH 7.4) containing 50% glycerol, 0.05% BSA and 0.02% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
NUP107 plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC. Involved in nephrogenesis[1][2][3].
-
Subcellular Localization
Nucleus membrane; Nucleus, nuclear pore complex; Chromosome, centromere, kinetochore
-
Expression
Tissue_Specificity: Ubiquitously expressed in fetal and adult tissues. -
Isoforms & Post-Translational Modification
NUP107 has 3 isoforms, P57740-1: amino acid length is 925, molecular weight is 106374 Da (predicted); P57740-2: amino acid length is 896, molecular weight is 103175 Da (predicted); P57740-3: amino acid length is 686, molecular weight is 79971 Da (predicted).
-
Subunit
Part of the nuclear pore complex (NPC).
-
SwissProt ID
-
Synonyms
Nucleoporin 107, Nuclear Pore Complex Protein Nup107, NUP84, Nucleoporin 107kDa, 107 KDa Nucleoporin, Nucleoporin Nup107, ODG6, GAMOS7, NPHS11, ODG6
Documentation
References
[1]. Boehmer T, et al. Depletion of a single nucleoporin, Nup107, prevents the assembly of a subset of nucleoporins into the nuclear pore complex. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):981-5. [Content Brief]
[2]. Krull S, et al. Nucleoporins as components of the nuclear pore complex core structure and Tpr as the architectural element of the nuclear basket. Mol Biol Cell. 2004 Sep;15(9):4261-77. [Content Brief]
[3]. Braun DA, et al. Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome. J Clin Invest. 2018 Oct 1;128(10):4313-4328. [Content Brief]
Powered by Bioz
