2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. OCT1 Antibody (YA5364)

OCT1 Antibody (YA5364) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to OCT1.

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容量 在庫状況
50 μL   お問い合わせ  
100 μL   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • 説明

製品説明

OCT1 Antibody (YA5364) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to OCT1.
Host

Mouse
Clonality

Monoclonal
分子量
Observed band size: 89 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

Synthetic Peptide of 42644
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-2000
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:200
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-300
純度 affinity chromatography. Conjugation Non-conjugated
Modification Unmodified  
Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
輸送条件

Shipping with blue ice.
Background
Function：P14859: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR; (Microbial infection) In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes
P09086: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') (PubMed:2904654, PubMed:7859290). Regulates IL6 expression in B cells with POU2AF1 (By similarity). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression (PubMed:2901913, PubMed:2904654). Modulates transcription transactivation by NR3C1, AR and PGR (PubMed:10480874) ; Activates the U2 small nuclear RNA (snRNA) promoter
Subcellular Localization：P14859: Nucleus
P09086: Cytoplasm; Nucleus
Expression：
Tissue_specificity: P14859: Ubiquitous. Isoform 2 is lymphocyte-specific
P09086: Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147
Subunit：P14859: Interacts with POU2AF1; the interaction increases POU2F1 transactivation activity (PubMed:7859290). Interacts with NR3C1, AR, PGR and HCFC1
P09086: Interacts with NR3C1, AR and PGR (PubMed:10480874). Interacts with POU2AF1; the interaction increases POU2F2 transactivation activity (PubMed:7859290)
ドキュメンテーション
User Guide for Antibodies (1077 KB)

OCT1 Antibody (YA5364) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
OCT1 Antibody (YA5364)
製品番号:
HY-P85672
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