OSGEP Antibody (YA8365)(PBS only)

(Synonyms: GCPL1; KAE1; OSGEP1; PRSMG1)

OSGEP Antibody (YA8365) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to OSGEP.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    WB, IHC-P, FC

  • Reactivity :

    Human, Dog, Rat, Mouse

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
FC Info
FC: Flow Cytometry
Dilution Ratio 1:500-2000 1:150-500 1:100

Product Details

Description

OSGEP Antibody (YA8365) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to OSGEP.

  • Host Mouse
  • Species Reactivity
    Human, Dog, Rat, Mouse
  • Calculated Molecular Weight Predicted band size: 36.2 kDa
Immunogen

Human recombinant protein fragment corresponding to amino acids 1-335 of human OSGEP produced in E.coli.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    OSGEP component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity

  • Subcellular Localization

    Cytoplasm,Nucleus

  • Expression


    Tissue_Specificity: Widely expressed at low level. Expressed in heart, placenta, liver, kidney, lung, brain, skeletal muscle and pancreas

  • Isoforms & Post-Translational Modification

    Q9NPF4: 335 amino acids, molecular weight 36427 Da.

  • Subunit

    Component of the EKC/KEOPS complex composed of at least GON7, TP53RK, TPRKB, OSGEP and LAGE3; the whole complex dimerizes

  • SwissProt ID

    Q9NPF4

  • Synonyms

    GCPL1; KAE1; OSGEP1; PRSMG1

OSGEP Antibody (YA8365)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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