OSGEP Antibody (YA8365)(PBS only)
(Synonyms: GCPL1; KAE1; OSGEP1; PRSMG1)OSGEP Antibody (YA8365) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to OSGEP.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
WB, IHC-P, FC
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Reactivity :
Human, Dog, Rat, Mouse
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:150-500 | 1:100 |
Product Details
OSGEP Antibody (YA8365) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to OSGEP.
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Host Mouse
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Species ReactivityHuman, Dog, Rat, Mouse
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Calculated Molecular Weight Predicted band size: 36.2 kDa
Human recombinant protein fragment corresponding to amino acids 1-335 of human OSGEP produced in E.coli.
Affinity purified
Non-conjugated
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
OSGEP component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity
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Subcellular Localization
Cytoplasm,Nucleus
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Expression
Tissue_Specificity: Widely expressed at low level. Expressed in heart, placenta, liver, kidney, lung, brain, skeletal muscle and pancreas -
Isoforms & Post-Translational Modification
Q9NPF4: 335 amino acids, molecular weight 36427 Da.
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Subunit
Component of the EKC/KEOPS complex composed of at least GON7, TP53RK, TPRKB, OSGEP and LAGE3; the whole complex dimerizes
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SwissProt ID
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Synonyms
GCPL1; KAE1; OSGEP1; PRSMG1
Documentation