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  4. PPM1B Antibody (YA7883)

PPM1B Antibody (YA7883) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PPM1B.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量 価格(税別) 在庫状況
20 μL $115 見積もりとリードタイムを求めるのご確認
50 μL $185 見積もりとリードタイムを求めるのご確認
100 μL $300 見積もりとリードタイムを求めるのご確認

* アイテムを追加する前、数量をご選択ください

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay
  • Product Detail

  • Background

  • 説明

製品説明

PPM1B Antibody (YA7883) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PPM1B.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 52.5 kDa

Species Reactivity
Human, Mouse, Rat
SwissProt ID
Immunogen

Full length human recombinant protein of human PPM1B produced in HEK293T cell.

Application &
Dilution Ratio
Application Dilution Ratio
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:100-250
FC
FC: Flow Cytometry
1:100
Sensitivity Endogenous 純度 Affinity purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG2a  
Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background
Function:Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB
Subcellular Localization:Cytoplasm, cytosol,Membrane
Expression:
Tissue_Specificity: Highly expressed in heart and skeletal muscle
Isoforms & Post-Translational Modification:O75688 has 5 isomers: O75688-1: 52643 Da (predicted); O75688-2: 42771 Da (predicted); O75688-3: 20753 Da (predicted); O75688-4: 42086 Da (predicted); O75688-5: 36313 Da (predicted).
Isgylation negatively regulates its activity丨N-myristoylation is essential for the recognition of its substrates for dephosphorylation
Subunit:Monomer (By similarity)
Synonyms
PP2C-beta; PP2C-beta-X; PP2CB; PP2CBETA; PPC2BETAX
ドキュメンテーション
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

製品名:
PPM1B Antibody (YA7883)
製品番号:
HY-P88199
数量:
MCE 日本正規代理店: