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Cat. No.: HY-P87586

PPM1E Antibody (YA7270)

PPM1E Antibody (YA7270) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPM1E.

For research use only. We do not sell to patients.

Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	FC FC: Flow Cytometry
Dilution Ratio	1:1000-2000	1:50-100

Description

PPM1E Antibody (YA7270) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPM1E.

Host Rabbit
Clonality Recombinant,Monoclonal
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 90 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 84 kDa

Immunogen

A synthesized peptide derived from human Protein phosphatase 1E

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

PPM1E is a Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2
Subcellular Localization

Nucleus,Cytoplasm
Isoforms & Post-Translational Modification

Q8WY54 has two isomers: Q8WY54-2: 83952 Da (predicted); Q8WY54-3: 58021 Da (predicted).
Subunit

Heterotrimer
SwissProt ID

Q8WY54