PRG2 Antibody
(Synonyms: MBP, PRG2, Bone marrow proteoglycan, BMPG, Proteoglycan 2)PRG2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to PRG2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:50-200 |
Product Details
PRG2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to PRG2.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 33; 31 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 25; 23 kDa
Purified recombinant protein of human PRG2
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PRG2 is a Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA
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Subcellular Localization
Secreted
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Expression
Tissue_Specificity: Detected in plasma and urine (at protein level). Detected in placenta (at protein level). High levels of the proform in placenta and pregnancy serum; in placenta, localized to X cells of septa and anchoring villi. Lower levels in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow and colon. -
Isoforms & Post-Translational Modification
PRG2 has 2 isoforms, P13727-1: amino acid length is 222, molecular weight is 25206 Da (predicted); P13727-2: amino acid length is 211, molecular weight is 23901 Da (predicted).可发生硝基化修饰PRG2 存在 2 个异构体，P13727-1：氨基酸个数为 222 个，分子量为 25206 Da (预测)；P13727-2：氨基酸个数为 211 个，分子量为 23901 Da (预测)。Nitrated
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Subunit
In pregnancy serum, the proform exists as a disulfide-linked 2:2 heterotetramer with PAPPA, as a disulfide-linked 2:2 heterotetramer with AGT, and as a complex (probably a 2:2:2 heterohexamer) with AGT and C3dg
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SwissProt ID
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Synonyms
MBP, PRG2, Bone marrow proteoglycan, BMPG, Proteoglycan 2
Documentation
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