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PRKAR1B (PKA regulatory subunit I beta) Antibody (YA8298)

(Synonyms: PRKAR1)

PRKAR1B (PKA regulatory subunit I beta) Antibody (YA8298) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRKAR1B (PKA regulatory subunit I beta).

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG

  • Application:

    IHC-P, ICC/IF, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Conjugation:
    Non-conjugated
  • PRKAR1B (PKA regulatory subunit I beta) Antibody (YA8298) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:150-500 1:100-250 1:100

Product Details

Description

PRKAR1B (PKA regulatory subunit I beta) Antibody (YA8298) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRKAR1B (PKA regulatory subunit I beta).

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 42.9 kDa
Immunogen

Full length human recombinant protein of human PRKAR1B produced in HEK293T cell.

Sensitivity

Endogenous

Purification

Affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    PRKAR1B is a Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells

  • Subcellular Localization

    Cell membrane

  • Expression


    Tissue_Specificity: Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible

  • Isoforms & Post-Translational Modification

    P31321: 381 amino acids, molecular weight 43073 Da.

  • Subunit

    The inactive holoenzyme is composed of two regulatory chains and two catalytic chains

  • SwissProt ID

    P31321

  • Synonyms

    PRKAR1

PRKAR1B (PKA regulatory subunit I beta) Antibody (YA8298) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • PRKAR1B (PKA regulatory subunit I beta) Antibody (YA8298) Product Image
    1/16
  • PRKAR1B (PKA regulatory subunit I beta) Antibody (YA8298) Product Image