RAB26 Antibody
(Synonyms: Ras-related protein Rab-26, RAB26)RAB26 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to RAB26.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-200 |
Product Details
RAB26 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to RAB26.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 28 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 27 kDa
Synthetic peptide corresponding to the C-term region of human RAB26.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
RAB26 is a The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB26 mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland (By similarity)[1][2].
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Subcellular Localization
Golgi apparatus membrane; Cytoplasmic vesicle, secretory vesicle membrane
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Expression
Tissue_Specificity: Predominantly expressed in brain. -
Isoforms & Post-Translational Modification
RAB26 has 2 isoforms, Q9ULW5-1: amino acid length is 256, molecular weight is 27900 Da (predicted); Q9ULW5-2: amino acid length is 190, molecular weight is 21355 Da (predicted).RAB26 存在 2 个异构体，Q9ULW5-1：氨基酸个数为 256 个，分子量为 27900 Da (预测)；Q9ULW5-2：氨基酸个数为 190 个，分子量为 21355 Da (预测)。
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Subunit
Interacts with RIMS1 (By similarity).
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SwissProt ID
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Synonyms
Ras-related protein Rab-26, RAB26
Documentation
[1]. Li C, et al. Rab26 modulates the cell surface transport of α2-adrenergic receptors from the Golgi. J Biol Chem. 2012 Dec 14;287(51):42784-94. [Content Brief]
[2]. Tian X, et al. RAB26 and RAB3D are direct transcriptional targets of MIST1 that regulate exocrine granule maturation. Mol Cell Biol. 2010 Mar;30(5):1269-84. [Content Brief]
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