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SLC2A5 (GLUT5) Antibody (YA7784)(PBS only)

(Synonyms: GLUT-5; GLUT5)

SLC2A5 (GLUT5) Antibody (YA7784) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC2A5 (GLUT5).

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P, ICC/IF, FC, IP

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • SLC2A5 (GLUT5) Antibody (YA7784)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
IP 2ug/500ul Info
 
Dilution Ratio 1:50-250 1:100-250 1:100

Product Details

Description

SLC2A5 (GLUT5) Antibody (YA7784) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC2A5 (GLUT5).

  • Host Mouse
  • Species Reactivity
    Human
  • Calculated Molecular Weight Predicted band size: 54.8 kDa
Immunogen

Full length human recombinant protein of human SLC2A5 produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    SLC2A5 functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of 2-deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake[1][2][3][4][5][6].

  • Subcellular Localization

    Apical cell membrane,Cell membrane,Cell membrane, sarcolemma

  • Expression


    Tissue_Specificity: Detected in skeletal muscle, and in jejunum brush border membrane and basolateral membrane (at protein level) (PubMed:7619085). Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue
    Induction: By forskolin in Caco-2 cells

  • Isoforms & Post-Translational Modification

    P22732 has two isomers: P22732-1: 54974 Da (predicted); P22732-2: 26519 Da (predicted).

  • SwissProt ID

    P22732

  • Synonyms

    GLUT-5; GLUT5

SLC2A5 (GLUT5) Antibody (YA7784)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • SLC2A5 (GLUT5) Antibody (YA7784)(PBS only) Product Image