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  5. Syntrophin alpha 1 Antibody (YA1828)

Syntrophin alpha 1 Antibody (YA1828)

Cat. No.: HY-P82083
COA
SDS
User Guide for Antibodies Technical Support

Syntrophin alpha 1 Antibody (YA1828) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Syntrophin alpha 1.

For research use only. We do not sell to patients.

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50 μL In-stock
100 μL In-stock
250 μL   Get quote  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

Syntrophin alpha 1 Antibody (YA1828) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Syntrophin alpha 1.
Host

Rabbit
Clonality

Recombinant,Monoclonal
Molecular Weight
Predicted band size: 54 kDa;
Observed band size: 54 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human Syntrophin alpha 1 aa1-53/505.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:1000-1:2000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:100-1:200
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:50-1:200
FC
FC: Flow Cytometry
1:50-1:100
Sensitivity Endogenous Purity Affinity Chromatography
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate (By similarity)
Subcellular Localization：Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side; Cell junction; Cytoplasm, cytoskeleton
Expression：
Tissue_specificity:High expression in skeletal muscle and heart. Low expression in brain, pancreas, liver, kidney and lung. Not detected in placenta
Isoforms & Post-Translational Modification：Q13424 has 2 isomers: Q13424-1: 53895 Da (predicted); Q13424-2: 45951 Da (predicted).
Phosphorylated by CaM-kinase II. Phosphorylation may inhibit the interaction with DMD (By similarity)
Subunit：Monomer and homodimer. Interacts with the other members of the syntrophin family SNTB1 and SNTB2; SGCG and SGCA of the dystrophin glycoprotein complex; NOS1; GRB2; the sodium channel proteins SCN4A and SCN5A; F-actin and calmodulin (By similarity). Interacts with dystrophin protein DMD and related proteins DTNA and UTRN and with MAPK12, TGFA and GA. Interacts with MYOC; regulates muscle hypertrophy (By similarity). Interacts with DTNB (By similarity)
Database

Entrez Gene: 6640 Human

SwissProt: Q13424 Human ; Q61234 Mouse ;

OMIM: 612955 Human

Research Field

Signal Transduction
Synonyms
Alpha 1 syntrophin; LQT12; SNT1; Snta1; Syntrophin 1; TACIP1
Documentation
SDS (252 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

Syntrophin alpha 1 Antibody (YA1828) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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