Syntrophin alpha 1 Antibody (YA1828)

Cat. No.: HY-P82083: Data Sheet COA
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User Guide for Antibodies
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Syntrophin alpha 1 Antibody (YA1828) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Syntrophin alpha 1.

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사이즈	재고	수량
20 μL	해외재고보유	Estimated Time of Arrival: December 31
50 μL	해외재고보유	Estimated Time of Arrival: December 31
100 μL	해외재고보유	Estimated Time of Arrival: December 31
250 μL	견적 받기

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Syntrophin alpha 1 Antibody (YA1828) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

Syntrophin alpha 1 Antibody (YA1828) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Syntrophin alpha 1.

Host

Rabbit

Clonality

Recombinant,Monoclonal

분자량

Predicted band size: 54 kDa;

Observed band size: 54 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse

SwissProt ID

Q13424

Gene ID

6640 [NCBI]

Immunogen

A synthesized peptide derived from human Syntrophin alpha 1 aa1-53/505.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
FC FC: Flow Cytometry	1:50-1:100

Sensitivity	Endogenous	Purity	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate (By similarity)

Subcellular Localization：Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side; Cell junction; Cytoplasm, cytoskeleton

Expression：
Tissue_specificity:High expression in skeletal muscle and heart. Low expression in brain, pancreas, liver, kidney and lung. Not detected in placenta

Isoforms & Post-Translational Modification：Q13424 has 2 isomers: Q13424-1: 53895 Da (predicted); Q13424-2: 45951 Da (predicted).
Phosphorylated by CaM-kinase II. Phosphorylation may inhibit the interaction with DMD (By similarity)

Subunit：Monomer and homodimer. Interacts with the other members of the syntrophin family SNTB1 and SNTB2; SGCG and SGCA of the dystrophin glycoprotein complex; NOS1; GRB2; the sodium channel proteins SCN4A and SCN5A; F-actin and calmodulin (By similarity). Interacts with dystrophin protein DMD and related proteins DTNA and UTRN and with MAPK12, TGFA and GA. Interacts with MYOC; regulates muscle hypertrophy (By similarity). Interacts with DTNB (By similarity)

Database

Entrez Gene: 6640 Human

SwissProt: Q13424 Human ; Q61234 Mouse ;

OMIM: 612955 Human

Research Field

Signal Transduction

Synonyms

Alpha 1 syntrophin; LQT12; SNT1; Snta1; Syntrophin 1; TACIP1

각종 서류

Select Batch:

Data Sheet (234 KB) SDS (252 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

Syntrophin alpha 1 Antibody (YA1828) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Syntrophin alpha 1 Antibody (YA1828)

Syntrophin alpha 1 Antibody (YA1828) Featured Recommendations:

Product Detail

Background

제품 설명

Syntrophin alpha 1 Antibody (YA1828) Related Classifications

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