gamma Synuclein/SNCG Antibody (YA5073)
(Synonyms: SNCG; BCSG1; PERSYN; PRSN; Gamma-synuclein; Breast cancer-specific gene 1 protein; Persyn; Synoretin; SR)gamma Synuclein/SNCG Antibody (YA5073) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to gamma Synuclein/SNCG.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB; IHC-P; IHC-F; ICC/IF; IF-Tissue; IP; FC
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Reactivity :
Human, Rat
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Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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IP
IP: Immunoprecipitation
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FC
FC: Flow Cytometry
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|---|---|---|---|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:100-200 | 1:50-200 | 1:50-200 | 1:20-50 | 1:50-100 |
Product Details
gamma Synuclein/SNCG Antibody (YA5073) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to gamma Synuclein/SNCG.
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Host Rabbit
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Clonality Monoclonal,Recombinant
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Species ReactivityHuman, Rat
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Observed Molecular WeightObserved band size: 16 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 13 kDa
A synthesized peptide derived from human gamma Synuclein. The exact sequence is proprietary to MCE.
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Livraison
Shipping with blue ice.
Background
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Function
gamma Synuclein/SNCG plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway
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Subcellular Localization
Cytoplasm, perinuclear region; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Cytoplasm, cytoskeleton, spindle
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Expression
Tissue_specificity:It is highly expressed in the brain, especially in the substantia nigra. It is also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon, and spleen. It is expressed less strongly in the pancreas, kidneys, and lungs. -
Subunit
May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation (By similarity)
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SwissProt ID
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Synonyms
SNCG; BCSG1; PERSYN; PRSN; Gamma-synuclein; Breast cancer-specific gene 1 protein; Persyn; Synoretin; SR
Documentation