gamma Synuclein/SNCG Antibody (YA5073)

Cat. No.: HY-P85381: Ficha de datos User Guide for Antibodies
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gamma Synuclein/SNCG Antibody (YA5073) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to gamma Synuclein/SNCG.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn
Referencias

Descripciòn

gamma Synuclein/SNCG Antibody (YA5073) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to gamma Synuclein/SNCG.

Host

Rabbit

Clonality

Monoclonal,Recombinant

Peso molecular

Predicted band size: 13 kDa;

Observed band size: 16 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Rat

SwissProt ID

O76070

Gene ID

6623 [NCBI]

Immunogen

A synthesized peptide derived from human gamma Synuclein. The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-200
IHC-F IHC-F: Immunohistochemistry-Frozen	1:100-200
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-200
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:50-200
IP IP: Immunoprecipitation	1:20-50
FC FC: Flow Cytometry	1:50-100

Sensitivity	Endogenous	Pureza	affinity purified by Protein A
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity)

Subcellular Localization：Cytoplasm, perinuclear region; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Cytoplasm, cytoskeleton, spindle

Expression：
Tissue_specificity:It is highly expressed in the brain, especially in the substantia nigra. It is also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon, and spleen. It is expressed less strongly in the pancreas, kidneys, and lungs.

Subunit：May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation (By similarity)

Synonyms

SNCG; BCSG1; PERSYN; PRSN; Gamma-synuclein; Breast cancer-specific gene 1 protein; Persyn; Synoretin; SR

Documentación

User Guide for Antibodies (1077 KB)

Referencias

[1]. /biology-dictionary/mda-mb-231-cell.html [Content Brief]