Themis Antibody (YA7028)
(Synonyms: C6orf190 antibody; C6orf207 antibody; MGC163388 antibody; Protein THEMIS antibody; SIGNALING PHOSPHOPROTEIN SPECIFIC FOR T CELLS antibody; SPOT antibody; THEMIS antibody; THMS1_HUMAN antibody; Thymocyte expressed molecule involved in selection antibody; Thymocyte selection associated antibody)Themis Antibody (YA7028) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Themis.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF, IHC-P, FC
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Reactivity :
Human, Rat
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Formulation:
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:50-1:100 | 1:50-1:200 | 1:50-1:100 |
Product Details
Themis Antibody (YA7028) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Themis.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Rat
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Observed Molecular WeightObserved band size: 73 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 73 kDa
Synthetic peptide within C-terminal Human Themis.
Endogenous
Protein A affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Envío
Shipping with blue ice.
Background
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Function
Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk
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Subcellular Localization
Cytoplasm,Nucleus
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Isoforms & Post-Translational Modification
Q8N1K5 has four isomers: Q8N1K5-1: 73452 Da (predicted); Q8N1K5-2: 69464 Da (predicted); Q8N1K5-3: 62568 Da (predicted); Q8N1K5-4: 77515 Da (predicted).
Phosphorylated on Tyr residues quickly after TCR stimulation -
Subunit
Interacts with PLCG1, ITK, GRB2, and LAT
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SwissProt ID
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Synonyms
C6orf190 antibody; C6orf207 antibody; MGC163388 antibody; Protein THEMIS antibody; SIGNALING PHOSPHOPROTEIN SPECIFIC FOR T CELLS antibody; SPOT antibody; THEMIS antibody; THMS1_HUMAN antibody; Thymocyte expressed molecule involved in selection antibody; Thymocyte selection associated antibody
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