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Transcription Factor 7 Like 1 Antibody (YA2794)

(Synonyms: Transcription factor 7-like 1; HMG box transcription factor 3; TCF-3; TCF7L1; TCF3)
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Transcription Factor 7 Like 1 Antibody (YA2794) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Transcription Factor 7 Like 1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, FC

  • Reactivity :

    Human

  • Formulation:

    Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

  • Conjugation:
    Non-conjugated
  • Transcription Factor 7 Like 1 Antibody (YA2794) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Data Download
Related Products:
Top Publications Citing

Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
FC Info
FC: Flow Cytometry
Dilution Ratio 1:1000-1:2000 1:50-1:100

Product Details

Description

Transcription Factor 7 Like 1 Antibody (YA2794) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Transcription Factor 7 Like 1.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 63 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 63 kDa
Species Reactivity Database

Entrez Gene: 83439 Human

SwissProt: Q9HCS4 Human

Immunogen

A synthesized peptide derived from human TCF3 aa71-123.

Sensitivity

Endogenous

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Transcription Factor 7 Like 1 participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. Down-regulates NQO1, leading to increased mitomycin c resistance

  • Subcellular Localization

    Nucleus

  • Expression


    Tissue_specificity:Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium

  • Subunit

    Binds the armadillo repeat of CTNNB1 and forms a stable complex (By similarity). Interacts with DAZAP2 (PubMed:19304756)

  • SwissProt ID

    Q9HCS4

  • Gene ID
    83439 [NCBI]
  • Synonyms

    Transcription factor 7-like 1; HMG box transcription factor 3; TCF-3; TCF7L1; TCF3

  • Research Field

    Epigenetics and Nuclear Signaling

Transcription Factor 7 Like 1 Antibody (YA2794) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • Transcription Factor 7 Like 1 Antibody (YA2794) Product Image
    1/16
  • Transcription Factor 7 Like 1 Antibody (YA2794) Product Image