TRIM2 Antibody (YA8002)
(Synonyms: CMT2R; RNF86)TRIM2 Antibody (YA8002) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TRIM2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
FC
FC: Flow Cytometry
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|---|---|
| Dilution Ratio | 1:100 |
Product Details
TRIM2 Antibody (YA8002) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TRIM2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 81.3 kDa
Human recombinant protein fragment corresponding to amino acids 1-100 and 1500-1600 of human SHPRH produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TRIM2 is an UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. Plays a role in antiviral immunity and limits New World arenavirus infection independently of its ubiquitin ligase activity[1].
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Subcellular Localization
Cytoplasm
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Isoforms & Post-Translational Modification
Q9C040 has two isomers: Q9C040-1: 81530 Da (predicted); Q9C040-2: 84545 Da (predicted).
RING-type zinc finger-dependent and UBE2D1-dependent autoubiquitination -
Subunit
Forms homooligomers (PubMed:36481767)
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SwissProt ID
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Synonyms
CMT2R; RNF86
Documentation
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