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  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. Tryptophan tRNA Ligase Antibody (YA1608)

Tryptophan tRNA Ligase Antibody (YA1608)

Cat. No.: HY-P81863
User Guide for Antibodies Technical Support

Tryptophan tRNA Ligase Antibody (YA1608) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Tryptophan tRNA Ligase.

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Size Prix Stock Quantité
20 μL Obtenir un devis 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Obtenir un devis 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Obtenir un devis 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Obtenir un devis  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Description

Description

Tryptophan tRNA Ligase Antibody (YA1608) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Tryptophan tRNA Ligase.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Masse moléculaire
Predicted band size: 53 kDa;
Observed band size: 53 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthetic peptide of human Tryptophanyl tRNA synthetase
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-1:100
IHC-F
IHC-F: Immunohistochemistry-Frozen
1:50-1:100
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:50-1:200
IP
IP: Immunoprecipitation
1:20
Sensitivity Endogenous Pureté Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Livraison

Shipping with blue ice.
Background
Function：Catalyzes the attachment of tryptophan to tRNA(Trp) in a two-step reaction: tryptophan is first activated by ATP to form Trp-AMP and then transferred to the acceptor end of the tRNA(Trp); Has no angiostatic activity; Possesses an angiostatic activity but has no aminoacylation activity (PubMed:11773625, PubMed:11773626, PubMed:14630953). Inhibits fluid shear stress-activated responses of endothelial cells (PubMed:14630953). Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression (PubMed:14630953); Has an angiostatic activity
Subcellular Localization：Cytoplasm
Expression：
Induction:By IFNG/IFN-gamma
Isoforms & Post-Translational Modification：P23381 has 2 isomers: P23381-1: 53165 Da (predicted); P23381-2: 48852 Da (predicted).
Proteolytic cleavage generates 2 forms; T1-TrpRS and T2-TrpRS
Subunit：Homodimer (PubMed:28369220). Interacts with an oxidized form of GAPDH. GAPDH stimulates the aminoacylation activity of isoform 2 (PubMed:15628863)
Database

Entrez Gene: 7453 Human

SwissProt: P23381 Human

OMIM: 617721 Human

Research Field

Epigenetics and Nuclear Signaling
Synonyms
Gamma2; hWRS; IFI53; IFP53; TrpRS; WARS; WRS
Documentation
User Guide for Antibodies (1077 KB)

Tryptophan tRNA Ligase Antibody (YA1608) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nom du produit:
Tryptophan tRNA Ligase Antibody (YA1608)
Cat. No.:
HY-P81863
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