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Cat. No.: HY-157027

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Antifungal agent 85

Antifungal agent 85 (compound 24f) is a potent antibacterial compound with the minimum inhibitory concentration (MIC) values between 2.5 and 10 μM against various Gram-positive bacteria.

For research use only. We do not sell to patients.

CAS No.: 3017207-42-7
Formula: C₂₃H₂₂F₃NO₃
Molecular Weight:417.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Antifungal agent 85 Chemical Structure

CAS No.: 3017207-42-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Antifungal agent 85 (compound 24f) is a potent antibacterial compound with the minimum inhibitory concentration (MIC) values between 2.5 and 10 μM against various Gram-positive bacteria^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	CC₅₀	>100 μM Compound: 24f	Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 24 hrs by resazurin staining based analysis Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 24 hrs by resazurin staining based analysis	[PMID: 37948883]
THP-1	CC₅₀	>100 μM Compound: 24f	Cytotoxicity against human THP-1 cells assessed as reduction in cell viability incubated for 24 hrs by resazurin staining based analysis Cytotoxicity against human THP-1 cells assessed as reduction in cell viability incubated for 24 hrs by resazurin staining based analysis	[PMID: 37948883]

Chemical Information

CAS No. 3017207-42-7
Molecular Weight 417.42
Formula C₂₃H₂₂F₃NO₃
SMILES

O=C(C(N1)=CC2=C1C=CC(OCC3=CC=C(C4CCCCC4)C(C(F)(F)F)=C3)=C2)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zore M, et al. Design and synthesis of etrasimod derivatives as potent antibacterial agents against gram-positive bacteria[J]. European Journal of Medicinal Chemistry, 2023: 115921.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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