2. Anti-infection
  3. HCV
  4. Antiviral agent 44

Antiviral agent 44 (compound 7b) is an antiviral agent that has anti-HCV activity in vitro.

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Antiviral agent 44

Antiviral agent 44 Chemical Structure

CAS No. : 872201-68-8

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Antiviral agent 44 Related Antibodies

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Description

Antiviral agent 44 (compound 7b) is an antiviral agent that has anti-HCV activity in vitro[1].

Cellular Effect
Cell Line Type Value Description References
Huh-7 CC50
> 100 μM
Compound: 4
Cytotoxicity against Huh7 cells after 24 hrs by MTS assay
Cytotoxicity against Huh7 cells after 24 hrs by MTS assay
[PMID: 17521911]
Huh-7 EC50
22 μM
Compound: 4
Antiviral activity against HCV genotype 1b in Huh7 cells assessed as inhibition of viral RNA replication after 24 hrs by ribonuclease protection assay
Antiviral activity against HCV genotype 1b in Huh7 cells assessed as inhibition of viral RNA replication after 24 hrs by ribonuclease protection assay
[PMID: 17521911]
Huh-7 EC50
8.1 μM
Compound: 4
Antiviral activity against HCV genotype 1b in Huh7 cells assessed as inhibition of viral RNA replication after 72 hrs by ribonuclease protection assay
Antiviral activity against HCV genotype 1b in Huh7 cells assessed as inhibition of viral RNA replication after 72 hrs by ribonuclease protection assay
[PMID: 17521911]
Molecular Weight

281.26

Formula

C12H15N3O5
CAS No.
SMILES

O[C@H]1[C@](O)(C)[C@H](C2=COC3=C2N=CN=C3N)O[C@@H]1CO
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antiviral agent 44 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antiviral agent 44872201-68-8Antiviral agent44Antiviral agent-44HCVHepatitis C virusAntiviral AgentAntibioticRNA polymeraseInhibitorinhibitorinhibit

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Antiviral agent 44
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HY-157291
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