2. PROTAC Vitamin D Related/Nuclear Receptor
  3. Ligands for Target Protein for PROTAC Androgen Receptor
  4. AR ligand-48

AR ligand-48 is an AR (Androgen Receptor) inhibitor and a ligand for the target protein for PROTAC (AR). AR ligand-48 can be used to synthesize PROTAC AR Degrader-12 (HY-179433).

For research use only. We do not sell to patients.

AR ligand-48

AR ligand-48 Chemical Structure

CAS No. : 1318208-88-6

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AR ligand-48 Related Antibodies

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Description

AR ligand-48 is an AR (Androgen Receptor) inhibitor and a ligand for the target protein for PROTAC (AR). AR ligand-48 can be used to synthesize PROTAC AR Degrader-12 (HY-179433)[1].

IC50 & Target

AR

 

In Vitro

AR PROTAC contains two different ligands connected by a linker; one is an E3 ligase ligand ((S,S,S)-AHPC-Me) (Compound D2) (HY-112078), and the other is for Ligands of AR target protein (AR ligand-48) (HY-179442). PROTAC exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AR ligand-48 Related Antibodies
Molecular Weight

444.48

Formula

C23H28N2O7
CAS No.
SMILES

COC(C1=CC(OCC(C)C)=C(C=C1)NC(C2=CC(OCC(C)C)=C(C=C2)[N+]([O-])=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AR ligand-48 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AR ligand-481318208-88-6AR ligand48AR ligand 48Ligands for Target Protein for PROTACAndrogen ReceptorTarget Protein-binding MoietyPROTACAREndocrine ResistanceBreast CancerInhibitorinhibitorinhibit

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AR ligand-48
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HY-179442
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