Arecaidine propargyl ester hydrobromide

Cat. No.: HY-134061 Purity: 99.47%: Data Sheet
COA

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Arecaidine propargyl ester hydrobromide is an agonist of M2 muscarinic acetylcholine receptors and has the activity of inhibiting tumor cell proliferation. The application of arecaidine propargyl ester hydrobromide has shown that it can reduce the number of ovarian cancer cells in vitro and induce apoptosis and the production of reactive oxygen species (ROS) at specific concentrations. Arecaidine propargyl ester hydrobromide can also arrest cells at the G2/M phase of the cell cycle and increase the percentage of abnormal mitosis. Arecaidine propargyl ester hydrobromide is more sensitizing to ovarian surface epithelial cells with higher M2 receptor levels than to cancer cells. Arecaidine propargyl ester hydrobromide exhibits the effect of lowering arterial blood pressure when interacting with the cardiovascular system in a natural physiological state, indicating its potential pharmacological application.

For research use only. We do not sell to patients.

Arecaidine propargyl ester hydrobromide Chemical Structure

CAS No. : 116511-28-5

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
250 mg	In-stock	Estimated Time of Arrival: December 31
500 mg	Get quote
1 g	Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Molecular Weight

260.13

Formula

C₁₀H₁₄BrNO₂

CAS No.

116511-28-5

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CCCN(C1)C)OCC#C.Br

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (384.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.8442 mL	19.2212 mL	38.4423 mL
5 mM	0.7688 mL	3.8442 mL	7.6885 mL
10 mM	0.3844 mL	1.9221 mL	3.8442 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.47%

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Data Sheet (268 KB) SDS (392 KB)

COA (246 KB) HNMR (247 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. The activation of M2 muscarinic receptor inhibits cell growth and survival in human epithelial ovarian carcinoma [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.8442 mL	19.2212 mL	38.4423 mL	96.1058 mL
	5 mM	0.7688 mL	3.8442 mL	7.6885 mL	19.2212 mL
	10 mM	0.3844 mL	1.9221 mL	3.8442 mL	9.6106 mL
	15 mM	0.2563 mL	1.2814 mL	2.5628 mL	6.4071 mL
	20 mM	0.1922 mL	0.9611 mL	1.9221 mL	4.8053 mL
	25 mM	0.1538 mL	0.7688 mL	1.5377 mL	3.8442 mL
	30 mM	0.1281 mL	0.6407 mL	1.2814 mL	3.2035 mL
	40 mM	0.0961 mL	0.4805 mL	0.9611 mL	2.4026 mL
	50 mM	0.0769 mL	0.3844 mL	0.7688 mL	1.9221 mL
	60 mM	0.0641 mL	0.3204 mL	0.6407 mL	1.6018 mL
	80 mM	0.0481 mL	0.2403 mL	0.4805 mL	1.2013 mL
	100 mM	0.0384 mL	0.1922 mL	0.3844 mL	0.9611 mL