Arecaidine propargyl ester hydrobromide
Based on 1 Customer Validation
Arecaidine propargyl ester hydrobromide is an agonist of M2 muscarinic acetylcholine receptors and has the activity of inhibiting tumor cell proliferation. The application of arecaidine propargyl ester hydrobromide has shown that it can reduce the number of ovarian cancer cells in vitro and induce apoptosis and the production of reactive oxygen species (ROS) at specific concentrations. Arecaidine propargyl ester hydrobromide can also arrest cells at the G2/M phase of the cell cycle and increase the percentage of abnormal mitosis. Arecaidine propargyl ester hydrobromide is more sensitizing to ovarian surface epithelial cells with higher M2 receptor levels than to cancer cells. Arecaidine propargyl ester hydrobromide exhibits the effect of lowering arterial blood pressure when interacting with the cardiovascular system in a natural physiological state, indicating its potential pharmacological application.
For research use only. We do not sell to patients.
- Purity: 99.47%
- CAS No.: 116511-28-5
- Formula: C10H14BrNO2
- Molecular Weight:260.13
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 116511-28-5
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Appearance Solid
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Molecular Weight 260.13
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Formula C10H14BrNO2
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Color White to off-white
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SMILES
O=C(C1=CCCN(C1)C)OCC#C.Br
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (384.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8442 mL | 19.2212 mL | 38.4423 mL | 96.1058 mL |
| 5 mM | 0.7688 mL | 3.8442 mL | 7.6885 mL | 19.2212 mL | |
| 10 mM | 0.3844 mL | 1.9221 mL | 3.8442 mL | 9.6106 mL | |
| 15 mM | 0.2563 mL | 1.2814 mL | 2.5628 mL | 6.4071 mL | |
| 20 mM | 0.1922 mL | 0.9611 mL | 1.9221 mL | 4.8053 mL | |
| 25 mM | 0.1538 mL | 0.7688 mL | 1.5377 mL | 3.8442 mL | |
| 30 mM | 0.1281 mL | 0.6407 mL | 1.2814 mL | 3.2035 mL | |
| 40 mM | 0.0961 mL | 0.4805 mL | 0.9611 mL | 2.4026 mL | |
| 50 mM | 0.0769 mL | 0.3844 mL | 0.7688 mL | 1.9221 mL | |
| 60 mM | 0.0641 mL | 0.3204 mL | 0.6407 mL | 1.6018 mL | |
| 80 mM | 0.0481 mL | 0.2403 mL | 0.4805 mL | 1.2013 mL | |
| 100 mM | 0.0384 mL | 0.1922 mL | 0.3844 mL | 0.9611 mL |