Asante potassium green-1 AM
Based on 1 Customer Validation
Asante potassium green-1 AM (APG-1 AM) is a cell-permeable K+-sensitive fluorescent indicator and potassium ion indicator that exhibits minimal interference from Na+ and pH at physiologically relevant intracellular levels. Asante potassium green-1 AM enables non-invasive monitoring and quantitative analysis of intracellular potassium ion concentrations (Ex/Em = 522/547 nm).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1369302-18-0
- 화학식: C55H62Cl2N2O20
- 분자량:1141.99
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Asante potassium green-1 AM (APG-1 AM) (12 μM; 40 min at 37°C) efficiently loads into primary mouse cortical astrocytes, enabling reliable measurement of resting intracellular K+ concentration[1].
Asante potassium green-1 AM (12 μM; 40 min at 37°C) reliably detects proportional increases in intracellular K+ concentration in primary mouse cortical astrocytes[1].
Asante potassium green-1 AM (12 μM; 40 min at 37°C) detects reversible, concentration-dependent drops in intracellular K+ concentration in primary mouse cortical astrocytes in response to glutamate, with an EC50 of 11.1 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1369302-18-0
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Appearance Solid
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분자량 1141.99
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화학식 C55H62Cl2N2O20
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SMILES
O=CC1=CC=C(N2CCOCCOCCN(CCOCCOCC2)C3=C(OC)C=C(C4=C5C=C(CCC(OCOC(C)=O)=O)C(C(Cl)=C5OC6=C4C=C(CCC(OCOC(C)=O)=O)C(OCOC(C)=O)=C6Cl)=O)C=C3)C(OC)=C1
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Synonyms
APG-1 AM
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Asante potassium green-1 AM
- 1369302-18-0
- APG-1 AM
- Fluorescent Dye
- intracellular potassium ion concentration
- pH
- membrane-permeant acetoxymethyl ester
- primary mouse cortical astrocytes
- cell-free intracellular-like solutions
- glutamate
- resting intracellular K+ concentration
- sodium ion
- potassium ion
- fluorescent indicator
- Inhibitor
- inhibitor
- inhibit