2,7-Dihydroxyxanthone
2,7-Dihydroxyxanthone is a xanthone compound that can be isolated from the aerial parts (stems and bark) of Mammea acuminata.
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- CAS. Nr.: 64632-72-0
- Formel: C13H8O4
- Molecular Weight:228.20
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| COLO 320 | IC50 |
91.2 μM
Compound: 3-21
|
Antiproliferative activity against human COLO320 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human COLO320 cells after 48 hrs by CCK8 assay
|
[PMID: 28376372] |
| HepG2 | IC50 |
>200 μM
Compound: 3-21
|
Antiproliferative activity against human HepG2 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human HepG2 cells after 48 hrs by CCK8 assay
|
[PMID: 28376372] |
| K562 | IC50 |
73.5 μM
Compound: 3-21
|
Antiproliferative activity against human K562 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human K562 cells after 48 hrs by CCK8 assay
|
[PMID: 28376372] |
| MCF7 | IC50 |
128.1 μM
Compound: 3-21
|
Antiproliferative activity against human MCF7 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human MCF7 cells after 48 hrs by CCK8 assay
|
[PMID: 28376372] |
| MDA-MB-231 | IC50 |
83.5 μM
Compound: 3-21
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Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by CCK8 assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by CCK8 assay
|
[PMID: 28376372] |
| Vero | CC50 |
36.5 μM
Compound: 13
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Cytotoxicity against African green monkey Vero cells after 4 days by MTT assay
Cytotoxicity against African green monkey Vero cells after 4 days by MTT assay
|
[PMID: 24679044] |
| Vero | IC50 |
12.2 μM
Compound: 13
|
Antiviral activity against Enterovirus 71 BrCr infected in African green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 4 days by MTT assay
Antiviral activity against Enterovirus 71 BrCr infected in African green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect after 4 days by MTT assay
|
[PMID: 24679044] |
Chemical Information
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CAS. Nr. 64632-72-0
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Appearance Solid
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Molecular Weight 228.20
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Formel C13H8O4
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SMILES
O=C1C2=CC(O)=CC=C2OC3=CC=C(C=C13)O
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Reinheit & Dokumentation
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Data Sheet (264 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)