93-O17S
Based on 1 Customer Validation
93-O17S is an ionizable lipid. 93-O17S is involved in the construction of LNP. 93-O17S can achieve mRNA delivery to the spleen.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.0%
- CAS. Nr.: 2227008-67-3
- Formel: C44H83N3O4S2
- Molecular Weight:782.28
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Speicherung:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vivo
Chemical Information
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CAS. Nr. 2227008-67-3
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Appearance Oil
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Molecular Weight 782.28
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Formel C44H83N3O4S2
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Color Light yellow to yellow
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SMILES
O=C(CCN(CCCN1C=NC=C1)CCC(OCCSCCCCCCCCCCCCCC)=O)OCCSCCCCCCCCCCCCCC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (127.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : ≥ 100 mg/mL (127.83 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Omo-Lamai S, et al. Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape Without Side Effects. bioRxiv [Preprint]. 2024 Apr 18:2024.04.16.589801. [Content Brief]
[2]. Delehedde C, et al. Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles. Pharmaceutics. 2021 Jun 24;13(7):945. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / Ethanol | 1 mM | 1.2783 mL | 6.3916 mL | 12.7831 mL | 31.9579 mL |
| 5 mM | 0.2557 mL | 1.2783 mL | 2.5566 mL | 6.3916 mL | |
| 10 mM | 0.1278 mL | 0.6392 mL | 1.2783 mL | 3.1958 mL | |
| 15 mM | 0.0852 mL | 0.4261 mL | 0.8522 mL | 2.1305 mL | |
| 20 mM | 0.0639 mL | 0.3196 mL | 0.6392 mL | 1.5979 mL | |
| 25 mM | 0.0511 mL | 0.2557 mL | 0.5113 mL | 1.2783 mL | |
| 30 mM | 0.0426 mL | 0.2131 mL | 0.4261 mL | 1.0653 mL | |
| 40 mM | 0.0320 mL | 0.1598 mL | 0.3196 mL | 0.7989 mL | |
| 50 mM | 0.0256 mL | 0.1278 mL | 0.2557 mL | 0.6392 mL | |
| 60 mM | 0.0213 mL | 0.1065 mL | 0.2131 mL | 0.5326 mL | |
| 80 mM | 0.0160 mL | 0.0799 mL | 0.1598 mL | 0.3995 mL | |
| 100 mM | 0.0128 mL | 0.0639 mL | 0.1278 mL | 0.3196 mL |
93-O17S Related Classifications
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