Arachidic acid-d2
Arachidic acid-d2 is the deuterium labeled Arachidic acid (HY-W004260). Arachidic acid (Eicosanoic acid) is a long-chain saturated fatty acid. Arachidic acid can be found in the human organism from the plasma phospholipid, fish, cannabis and other plant oils. Arachidic acid conjugated with Chitosan oligosaccharide (HY-112108) can be used for anti-cancer drug delivery research.
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- CAS. Nr.: 232600-70-3
- Formel: C20H38D2O2
- Molecular Weight:314.54
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Biologische Aktivität
Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 232600-70-3
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Unlabeled CAS 506-30-9
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Molecular Weight 314.54
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Formel C20H38D2O2
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SMILES
CCCCCCCCCCCCCCCCCCC([2H])([2H])C(O)=O
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Synonyms
Icosanoic acid-d2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Protocol for Fluorescence In Situ Hybridization (FISH)
Fluorescence in situ hybridization detects specific DNA or RNA sequences inside fixed cells or tissue sections by hybridizing fluorescently labeled nucleic-acid probes to complementary target sequences, allowing the target’s copy number, chromosomal position, spatial distribution, or transcript abundance to be visualized microscopically. DNA-FISH detects genomic loci, chromosomal gains/losses, amplifications, deletions, and rearrangements, while RNA-FISH detects RNA molecules or transcript localization; in cancer cells, mouse tumors, neurons, organoids, macrophages, or drug-screening samples, the readout is fluorescent puncta, fusion/split signals, or localized RNA signal interpreted relative to validated controls.
Reinheit & Dokumentation
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Cardoso LMB, et al. New polymorphic phase of arachidic acid crystal: structure, intermolecular interactions, low-temperature stability and Raman spectroscopy combined with DFT calculations. RSC Adv. 2023 Nov 21;13(48):34032-34044. [Content Brief]
[3]. Termsarasab U, et al. Chitosan oligosaccharide-arachidic acid-based nanoparticles for anti-cancer drug delivery. Int J Pharm. 2013 Jan 30;441(1-2):373-80. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Arachidic acid-d2 Related Classifications
HY-W004260S Related Classifications
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