Cimoxatone
Based on 1 Customer Validation
Cimoxatone (MD 780515) is a reversible, selectively and orally active type A monoamine oxidase (MAO-A) inhibitor. Cimoxatone enhances the anorectic action of Serotonin (HY-B1473A).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.03%
- CAS. Nr.: 73815-11-9
- Formel: C19H18N2O4
- Molecular Weight:338.36
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
MAO-A |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:250-300 g, Adult male Wistar rats[1]
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Dosage:20 mg/kg
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Administration:P.o.
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Result:Significiantly reduced sucrose intake induced by 1 mg/kg 5-HT or its vehicle injected 2 and 24 h later, significantly enhanced the anorectic action of 5-HT at 2 h but not at 24 h.
Chemical Information
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CAS. Nr. 73815-11-9
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Appearance Solid
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Molecular Weight 338.36
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Formel C19H18N2O4
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Color White to light yellow
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SMILES
N#CC1=CC=CC(COC2=CC=C(N3C(OC(COC)C3)=O)C=C2)=C1
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Synonyms
MD 780515
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (295.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (244 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9554 mL | 14.7772 mL | 29.5543 mL | 73.8858 mL |
| 5 mM | 0.5911 mL | 2.9554 mL | 5.9109 mL | 14.7772 mL | |
| 10 mM | 0.2955 mL | 1.4777 mL | 2.9554 mL | 7.3886 mL | |
| 15 mM | 0.1970 mL | 0.9851 mL | 1.9703 mL | 4.9257 mL | |
| 20 mM | 0.1478 mL | 0.7389 mL | 1.4777 mL | 3.6943 mL | |
| 25 mM | 0.1182 mL | 0.5911 mL | 1.1822 mL | 2.9554 mL | |
| 30 mM | 0.0985 mL | 0.4926 mL | 0.9851 mL | 2.4629 mL | |
| 40 mM | 0.0739 mL | 0.3694 mL | 0.7389 mL | 1.8471 mL | |
| 50 mM | 0.0591 mL | 0.2955 mL | 0.5911 mL | 1.4777 mL | |
| 60 mM | 0.0493 mL | 0.2463 mL | 0.4926 mL | 1.2314 mL | |
| 80 mM | 0.0369 mL | 0.1847 mL | 0.3694 mL | 0.9236 mL | |
| 100 mM | 0.0296 mL | 0.1478 mL | 0.2955 mL | 0.7389 mL |