NDBM
NDBM is a probe and binds to tumor-specific Pim-1 kinase, releases strong fluorescence, and produces cytotoxicity, thus achieving cell screening and killing effects. NDBM can specifically target lysosomes and sensitively respond to pH. NDBM can be used to track the pH changes in the intracellular environment under conditions of autophagy and external stimulation.
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- CAS. Nr.: 2958641-42-2
- Formel: C33H35BrN4O7
- Molecular Weight:679.56
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Pim-1[1]
NDBM (2.5, 5, 10 and 20 μM, 18 h) decreases the survival rate of tumor cells (MGC-803, HepG2 and Hela) [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2958641-42-2
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Molecular Weight 679.56
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Formel C33H35BrN4O7
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SMILES
BrC1=CC=C2OC(C(NCCOCCOCCN3C(C4=C5C(C(NCCN6CCOCC6)=CC=C5C3=O)=CC=C4)=O)=O)=CC2=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)