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Art. -Nr.: HY-185423

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PreQ1-DBCO

PreQ1-DBCO is a strained cyclooctyne commonly used in click chemistry. PreQ1-DBCO undergoes TGT-catalyzed guanine base exchange in DNA oligonucleotide stem-loops to replace guanine. PreQ1-DBCO functionalizes custom DNA oligonucleotide sequences. DBCO-modified DNA oligonucleotides are conjugated with azide peptides via strain-promoted azide-alkyne click chemistry (SPAAC). PreQ1-DBCO can be used in studies of hemophilia B (Christmas disease).

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₃₄H₃₉N₇O₃
Molecular Weight:593.72

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

PreQ1-DBCO Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

Alle DNA/RNA Synthesis Isoform-spezifische Produkte anzeigen :

Chemical Information

Molecular Weight 593.72
Formel C₃₄H₃₉N₇O₃
SMILES

O=C(NCCCCCCNCC1=CNC(N=C(N2)N)=C1C2=O)CCCCC(N3CC4=C(C#CC5=C3C=CC=C5)C=CC=C4)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Mohamedshah ZY, et al. Highly efficient expression of DNA-peptide conjugates in growth-arrested cells. Nat Commun. 2026;17(1):1422. Published 2026 Jan 7. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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