Propyl dodecanoate
Based on 1 Customer Validation
Propyl dodecanoate (Propyl laurate) is a synthetic dodecanoic acid ester, exhibiting biting deterrent activity against Aedes aegypti mosquitoes. Propyl dodecanoate can be used for the research of mosquito-borne disease vectors (Aedes aegypti).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.83%
- CAS. Nr.: 3681-78-5
- Formel: C15H30O2
- Molecular Weight:242.40
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Speicherung:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
Propyl dodecanoate (Compound 2c) (25 nmol/cm2) exhibits a BDI (biting deterrent index) value of 0.92 in the in vitro K&D bioassay[2].
Propyl dodecanoate (50-100 μg/cm2) exhibits a MED (minimum effective dosage) value of 100 μg/cm2 in the in vitro K&D bioassay[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 3681-78-5
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Appearance Liquid (Density: 0.86 g/cm3)
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Molecular Weight 242.40
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Formel C15H30O2
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Color Colorless to light yellow
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SMILES
CCCCCCCCCCCC(OCCC)=O
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Synonyms
Propyl laurate
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (412.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (20.63 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Reinheit & Dokumentation
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Data Sheet (266 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Domínguez de María P, et al. Unexpected reaction profile observed in the synthesis of propyl laurate when using Candida rugosa lipases immobilized in microemulsions based organogels. Biotechnol Lett. 2004;26(19):1517-1520. [Content Brief]
[2]. Cantrell CL, et al. Biting deterrency of undecanoic acid and dodecanoic acid ester analogs against Aedes aegypti. Pest Manag Sci. 2021;77(8):3737-3743. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 4.1254 mL | 20.6271 mL | 41.2541 mL | 103.1353 mL |
| 5 mM | 0.8251 mL | 4.1254 mL | 8.2508 mL | 20.6271 mL | |
| 10 mM | 0.4125 mL | 2.0627 mL | 4.1254 mL | 10.3135 mL | |
| 15 mM | 0.2750 mL | 1.3751 mL | 2.7503 mL | 6.8757 mL | |
| 20 mM | 0.2063 mL | 1.0314 mL | 2.0627 mL | 5.1568 mL | |
| 25 mM | 0.1650 mL | 0.8251 mL | 1.6502 mL | 4.1254 mL | |
| 30 mM | 0.1375 mL | 0.6876 mL | 1.3751 mL | 3.4378 mL | |
| 40 mM | 0.1031 mL | 0.5157 mL | 1.0314 mL | 2.5784 mL | |
| 50 mM | 0.0825 mL | 0.4125 mL | 0.8251 mL | 2.0627 mL | |
| 60 mM | 0.0688 mL | 0.3438 mL | 0.6876 mL | 1.7189 mL | |
| 80 mM | 0.0516 mL | 0.2578 mL | 0.5157 mL | 1.2892 mL | |
| 100 mM | 0.0413 mL | 0.2063 mL | 0.4125 mL | 1.0314 mL |
Propyl dodecanoate Related Classifications
HY-W002270 Related Classifications
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