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Art. -Nr.: HY-105164

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Topixantrone

(Synonyms: BBR 3576)

Topixantrone (BBR 3576) is an antitumor agent, and shows antitumor activity on prostate carcinoma.

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CAS. Nr.: 156090-18-5
Formel: C₂₁H₂₆N₆O₂
Molecular Weight:394.47

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Topixantrone Chemical Structure

CAS. Nr.: 156090-18-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Topixantrone (BBR 3576) is an antitumor agent, and shows antitumor activity on prostate carcinoma^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
LoVo	IC₅₀	0.3 μg/mL Compound: 13x	In vitro cytotoxicity on human colon adenocarcinoma (LoVo ) tumor cell line. In vitro cytotoxicity on human colon adenocarcinoma (LoVo ) tumor cell line.	[PMID: 9876113]
LoVo	IC₅₀	57 μg/mL Compound: 13x	In vitro cytotoxicity on human colon adenocarcinoma resistant to doxorubicin (LoVo/Dx ) tumor cell line. In vitro cytotoxicity on human colon adenocarcinoma resistant to doxorubicin (LoVo/Dx ) tumor cell line.	[PMID: 9876113]

Chemical Information

CAS. Nr. 156090-18-5
Molecular Weight 394.47
Formel C₂₁H₂₆N₆O₂
SMILES

O=C1C2=C(C3=NN(CCNCCO)C4=CC=C(C1=C34)NCCN(C)C)C=NC=C2
Synonyms

BBR 3576
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Lori A. Hazlehurst, et al. Investigations on the Mechanisms of Resistance to Pixantrone in Tumor Cells. Blood (2004) 104 (11): 3402.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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