YM-49598 iodide
YM-49598 iodide is a tachykinin NK-1 receptor antagonist. YM-49598 iodide can inhibit drug-induced bladder contraction in rats, with IC50 of 11 μg/kg.
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- CAS. Nr.: 476494-44-7
- Formel: C36H45Cl2IN2O2
- Molecular Weight:735.57
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
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NK1R |
Chemical Information
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CAS. Nr. 476494-44-7
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Molecular Weight 735.57
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Formel C36H45Cl2IN2O2
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SMILES
CC(C)OC1=CC(CC(N2CC(C3=CC=C(C(Cl)=C3)Cl)(CCC2)CC[N+]4(CCC(CC4)C5=CC=CC=C5)C)=O)=CC=C1.[I-]
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)