(Z)-Broparestrol
(Z)-Broparestrol is a prostaglandin synthetase inhibitor with an IC50 of 7.0 μM in cattle. (Z)-Broparestrol inhibits prostaglandin synthetase activity in bovine seminal vesicle microsomes. (Z)-Broparestrol is applicable for acne-related research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 22393-63-1
- Formel: C22H19Br
- Molecular Weight:363.29
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
(Z)-Broparestrol (BROPARESTROL Z) inhibits prostaglandin synthetase activity in bovine seminal vesicle microsomes with an IC50 of 7.0 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 22393-63-1
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Molecular Weight 363.29
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Formel C22H19Br
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SMILES
Br/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)\C3=CC=C(C=C3)CC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Gilbert J, et al. Inhibition of prostaglandin synthetase by di- and triphenylethylene derivatives: a structure-activity study. Journal of medicinal chemistry. 1983 May;26(5):693-9. [Content Brief]
[2]. Toscani S, et al. Overt and hidden polymorphism in the binary system involving the Z- and E- isomers of broparestrol. Int J Pharm. 2025 Jan 25;669:125060. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)